Circadian rhythm in spinocerebellar ataxia type 3: clinical and actigraphy evaluation
circadian rhythm, actigraphy, neurodegenerative diseases, ataxia
spinocerebellar, spinocerebellar ataxia type 3, SCA 3, machado-joseph disease
ABSTRACT: The relationship between circadian rhythm and neurodegenerative diseases comes from
being studied with increasing interest, since it seems to be a promising avenue
for the understanding of the neurodegenerative process and, perhaps, can contribute to the
development of neuroprotective therapeutic strategies. Currently, there are studies in
Circadian rhythm in some types of neurodegenerative diseases such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease; however, still
There are no published studies on circadian aspects of people with ataxias
spinocerebellar. This is an observational case-control study that aims to
Objective: To evaluate circadian rhythms and sleep disturbances in patients diagnosed with
type 3 spinocerebellar ataxia through specific questionnaires validated in the
literature and actigraphy analysis and compare with patients who do not have
Diagnosis of spinocerebellar ataxia type 3 in the control group. To date,
were evaluated