Banca de DEFESA: DANIGLAYSE SANTOS VIEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : DANIGLAYSE SANTOS VIEIRA
DATE: 28/06/2021
TIME: 15:00
LOCAL: Sala Virtual - https://meet.google.com/ojm-bjov-ykm
TITLE:

ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF LATEX IN NATURA AND LYOPHILIZED FROM Jatropha multifida L.: in vitro study

KEY WORDS:

Jatropha multifida, Antioxidant Activity, Antimicrobial Activity

PAGES: 62
BIG AREA: Ciências da Saúde
AREA: Enfermagem
SUMMARY:

Jatropha multifida or Adenoropium multifidum (synonymy), popularly known as coral plant, coral, coral flower, blood flower, balsam, mertiolate, a shrub whose red flowers with yellowish anthers look like small pieces of coral and stem with latex presence. Widely used in folk medicine, as a purgative, against gonorrhea, diuretic, healing and anti-inflammatory. The aim of this research was to verify the antioxidant and antimicrobial activity of in natura and lyophilized latex from J. multifida. The latex was collected in the city of Igreja Nova/AL and was later submitted to the lyophilization process, thus originating the in natura and lyophilized extracts used in the study. Phytochemical prospection, antioxidant activity and antimicrobial activity tests were performed. The phytochemical activity of the latex extracts performed confirmed the presence of saponins, flavonoids, anthraquinones and tannins. The results showed that the in natura and freeze-dried latex extract showed moderate antioxidant activity, and can be considered as a promising source of fighting free radicals, but the values found in the freeze-dried latex (73.1 μg/mL) were more expressive in the concentration a 5% than in natura latex (84.5 μg/mL). For antimicrobial activity, both extracts presented a MIC of 15.6 μg mL-1 and a CBM of 125 μg mL-1 against S. epidermidis and E. faecalis, E. aerogenes same values for the MIC extracts of 125 μg mL-1 and 125 μg ml-1 CBM. For S. aureus the MIC was the same for both extracts of 125 μg mL-1, however, the CBM was better in the lyophilized with the same MIC value, the same happened with P. aeruginosa. Against E. coli, the lyophilized latex showed a better 125 μg mL-1 MIC, but in natura latex showed a better 125 μg mL-1 CBM activity in CBM. Already against the fungal strain C. albicans both extracts showed weak activity for both MIC which was 500 μg mL-1 and CBM 1000 μg mL-1. It is concluded that the in natura and lyophilized latex of J. multifida can be considered potential antimicrobial and antioxidant agents, but the lyophilized latex showed the best results in the tests performed, being a promising one to be used in future researches.

BANKING MEMBERS:
Presidente - 2121176 - MARIA LYSETE DE ASSIS BASTOS
Externa ao Programa - 2422344 - PATRICIA DE ALBUQUERQUE SARMENTO
Interna - 1490861 - ROSSANA TEOTONIO DE FARIAS MOREIRA