Banca de DEFESA: DAVI PORFIRIO DA SILVA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : DAVI PORFIRIO DA SILVA
DATE: 20/07/2022
TIME: 09:00
LOCAL: Sala Virtual - https://meet.google.com/hjz-yfua-bdv
TITLE:

EPIDEMIOLOGICAL PROFILE OF INDIVIDUALS WITH CHRONIC WOUNDS AND SCREENING FOR OXACILLIN-RESISTANT Staphylococcus aureus

KEY WORDS:

Chronic Wounds; Wound Healing; Staphylococcus aureus.

PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Enfermagem
SUMMARY:

Wounds are a health problem whose biopsychosocial impacts can be exacerbated by delayed healing, a multifactorial process that includes damage related to infections. Among the main infectious agents in wounds, the Staphylococcus aureus species stands out, a microorganism recognized for its antimicrobial resistance capacity, as occurs with oxacillin-resistant S. aureus. In this sense, the present study aimed to characterize the epidemiological profile of individuals with chronic lesions and to track oxacillin-resistant Staphylococcus aureus. This is a cross-sectional, quantitative, descriptive study carried out with individuals undergoing outpatient follow-up for the treatment of chronic wounds. The study included 53 adults of both sexes, who had wounds with an evolution time equal to or greater than six weeks. The collection of sociodemographic data and clinical aspects took place through interviews, consultations with medical records and evaluation of the lesion. The biological material was collected with a sterile swab and the isolated microorganisms were submitted to biochemical tests and cultured in a selective-differential medium for presumptive identification. The determination of the Minimum Inhibitory Concentration was carried out using the broth microdilution technique. The statistical analysis of the results took place in a descriptive manner. From the analysis of sociodemographic and clinical data, there was a higher frequency of female individuals (58.49%), self-declared brown (47.17%), with a mean age of 59.6 years, incomplete elementary school (43 .40%), dependent on social/social security benefits (84.91%) and residing in Maceió (69.81%). In addition, most participants (90.57%) reported comorbidities, with systemic arterial hypertension and diabetes mellitus being more frequent; reports of smoking (7.55%), routine use of alcohol (3.77%) and hospitalization in the last 12 months (20.75%) were less frequent. Regarding the clinical characteristics of the lesion, there was a higher frequency of individuals with wounds smaller than 10cm2 (33.96%) and between 10 and 50cm2 (32.08%), 10 years or more of evolution (37.74%), single lesion (56.60%), classified as venous ulcer (64.15%) and located in the lower limbs (96.23%). In addition, the presence of unfavorable signs in the evaluation of the perilesional skin (64.15%) and edge (60.38%) prevailed, as well as the presence of signs of infection (56.60%); however, the presence of favorable signs, such as the presence of only viable tissue in the wound bed (62.26%), and little (41.51%) or moderate (43.40%) volume of exudate, of the serous type ( 84.91%), were also frequent. The use of systemic antimicrobials was reported by 3.77% of the participants, although all (100%) used topical antimicrobials. The presumptive identification confirmed the presence of eight strains of S. aureus, from seven lesions/participants. Most of the isolates (75%) were sensitive to the lowest concentration of oxacillin evaluated (3.90ug/ml), although two isolates (25%) were resistant to oxacillin (62.5ug/ml and 500ug/ml). The sociodemographic and clinical profile of the participants consisted mainly of female individuals, mixed race, with incomplete primary education and dependent on social security benefits, who reported comorbidities, especially hypertension and diabetes. In addition, wounds with 10 years or more of evolution, located in the lower limbs and classified as venous ulcers were frequent. Screening and determination of antimicrobial susceptibility made it possible to detect two oxacilian-resistant clinical strains of S. aureus.

BANKING MEMBERS:
Externa à Instituição - LARA MENDES DE ALMEIDA
Presidente - 1490861 - ROSSANA TEOTONIO DE FARIAS MOREIRA
Externo ao Programa - 1653165 - VALTER ALVINO DA SILVA