Banca de DEFESA: NATALIA MENDES DE MELO MACHADO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : NATALIA MENDES DE MELO MACHADO
DATE: 28/03/2024
TIME: 16:00
LOCAL: meet.google.com/sgz-mngr-jue
TITLE:

Association between 25-hydroxyvitamin D and functional capacity in elderly people from Alagoas.

KEY WORDS:

Aging; 25-hydroxyvitamin D; Hand strength; Daily Activities.

PAGES: 66
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Aging changes such as decreased visual and hearing acuity, nutritional changes, less physical activity, the emergence of chronic non-communicable diseases and the use of medications may be related to decreased functional capacity in elderly people. Furthermore, 25-hydroxyvitamin D deficiency, considered a public health problem and highly prevalent in elderly people, also appears to contribute to functional disability. It is known that this micronutrient influences the integrity of components of the musculoskeletal system and central nervous system, closely related to functional aspects. However, there are still controversial results when analyzing the relationship between 25-hydroxyvitamin D deficiency and functional disability. Aiming to contribute to the discussion of the problem, this dissertation is structured into three sections, a presentation chapter, a literature review chapter and a chapter composed of an original scientific article. The original article entitled The association between 25-hydroxyvitamin d deficiency and functional disability in the elderly is mediated by muscle mass aimed to evaluate the association between 25-hydroxyvitamin D deficiency and functional disability, taking the circumference of the calf and muscle strength as mediators of the association. This is a cross-sectional study, carried out in the state of Alagoas, which included elderly people of both sexes and community residents, participants in a macro project, with non-probabilistic convenience sampling. All participants who had 25-hydroxyvitamin D tests were included in the study. Functional capacity was assessed using KATZ scale scores that assess independence in carrying out basic activities of daily living. Muscle mass was assessed by calf circumference and muscle strength was assessed by handgrip strength. The sample consisted of 468 individuals, with a mean age of 70.8 ± 8.08 years, the majority of whom were women (69.9%; n=327). 30.1% (n=141) of participants had low strength and 33.8% (n=158) had inadequate calf circumference. Vitamin D deficiency was present in 12.2% (n=57) of the sample and 19% (n=89) had functional disability. Using linear regression, adjusted for sex, age and BMI, 25-hydroxyvitamin D deficiency was associated with the outcome variables: muscle mass, muscle strength and functional capacity. Vitamin D deficiency was a predictor of calf circumference (β=-0.8 [-1.6; -0.02]) and functional disability (β=0.27 [0.08; 0.46], but not muscle strength (β=0.81 [-2.69; 1.07]. Muscle mass, assessed by calf circumference, mediated the effect of vitamin D deficiency on functional capacity (Indirect effect β=0.04 [0.003;0.107]).

COMMITTEE MEMBERS:
Presidente - 1727406 - JOAO ARAUJO BARROS NETO
Externo(a) ao Programa - 3621153 - JULIANA CELIA DE FARIAS SANTOS - nullInterno(a) - 1130431 - NASSIB BEZERRA BUENO