Banca de DEFESA: JEFFERSON FALCAO DA SILVA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : JEFFERSON FALCAO DA SILVA
DATE: 27/04/2023
TIME: 09:00
LOCAL: https://meet.google.com/ojp-qmwc-mmv
TITLE:

Analysis of whole blood amino acid concentrations in elite karate athletes.

KEY WORDS:

Amino Acids; Exercise; Metabolism; Sportomics.

PAGES: 79
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Sportomics is developed in a scenario where samples, usually blood and urine, are collected in loco, directly on the competition and training fields, simulating the real challenges and conditions faced during sports performances. Its application within metabolomics establishes the study of changes in athletes' metabolism, providing information on what is happening at the cellular level in response to factors such as: diet, lifestyle, drug use and disease. The objective of this study was to analyze the metabolism of amino acids (AAs) in elite national karate athletes, during a training session, using the sportomic approach. Seven karatekas (3 male and 4 female), in their preparation for the XVII Pan American Games in 2015, held in Toronto, Canada, participated in a training session. Blood samples were collected immediately before and after the training session, imitating a real competition situation (kata), and analyzed using mass spectrometry (MS). The results showed the presence of 21 AAs, subdivided into: aromatic AAs (AAA), branched-chain AAs (BCAA), ketogenic AAs (KAA), glucoketogenic AAs (GKAA), glycogenic AAs (GAA) and total AAs (AAt). When results were stratified by gender, ornithine increased significantly for female athletes (P = 0.01). Male athletes demonstrated a significant increase in the amino acid threonine (P = 0.009). A percentage analysis showed that the amino acid arginine increased for both sexes: female 51.55%; male 39.64%. Also, GAA values (-12.52%) for females and GAA (11.89%) for males were high. This study generated data on AAs concentrations, as well as principles and procedures to obtain data in metabolomics and proteomics studies, within the sportomics approach. Furthermore, based on their metabolic profiles, both sexes could opt for tailored physical training to preserve, improve health and performance.

BANKING MEMBERS:
Presidente - 1878467 - GUSTAVO GOMES DE ARAUJO
Externo(a) ao Programa - 1653558 - LUCIANO APARECIDO MEIRELES GRILLO
Interno(a) - 1311365 - THAYS DE ATAIDE E SILVA