Banca de DEFESA: RAFAEL LUIS BARROS DE OLIVEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : RAFAEL LUIS BARROS DE OLIVEIRA
DATE: 29/04/2024
TIME: 10:00
LOCAL: Sala da pós-graduação do IQB
TITLE:

Evaluation of the antiglycant, antioxidant and photoprotective potential
of ethanol extracts from the bark and seed of jabuticaba (Plinia
cauliflora)

KEY WORDS:

Jabuticaba; carbonyl stress; glycation; photoprotection

PAGES: 80
BIG AREA: Ciências Exatas e da Terra
AREA: Química
SUMMARY:

‘‘Jabuticaba (Plinia Cauliflora) is a fruit native to Brazil with high
antioxidant potential and its consumption is correlated with a lower risk
of the appearance of several chronic neurodegenerative diseases. They,
in turn, are related to a poor quality of life in general of the population
and chronic exposure to ultraviolet radiation (UV), causing an imbalance
between the production of reactive species and the antioxidant system,
that is, oxidative stress and the carbonyl. This work seeks to take
advantage of the residues (bark and seed) in order to evaluate the
antioxidant, antiglicante and photoprotective potential. The antioxidant
potential was evaluated by the DPPH•, FRAP, O2•˗ and HOCl assays,
the Antiglycant potential was evaluated in the BSA/glucose+fructose and
Hemoglobin/glucose+fructose systems, changes in the Soret band and
blood fibrillation were also evaluated. hemoglobin, the photoprotective
potential was evaluated by the Mansur method. Thus, the extracts
showed antioxidant activity for the methods used, protected the Soret
band against Glycation, bloomed with the BSA System in the same
region of the AGEs, showed a photoprotective effect with SPF > 6 for
both the extracts and the formulations containing only the extracts and
the formulations incorporated with benzophenone-3. Therefore, the
inhibition of the extract against the glycation of proteins that generates
advanced glycation products (AGEs) which cause various diseases with
changes in biomolecules.

COMMITTEE MEMBERS:
Presidente - 1006306 - JADRIANE DE ALMEIDA XAVIER
Interno(a) - 1613338 - JOSUE CARINHANHA CALDAS SANTOS
Interno(a) - 2120103 - MARILIA OLIVEIRA FONSECA GOULART
Externo(a) à Instituição - THAISSA LUCIO SILVA - IFAL