Banca de QUALIFICAÇÃO: PAULO RICARDO DOS SANTOS CORREIA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : PAULO RICARDO DOS SANTOS CORREIA
DATE: 30/08/2021
TIME: 09:00
LOCAL: Google Meet
TITLE:

Planning, Synthesis and Analysis of Potential Inhibitors from Morita-Baylis-Hillman Adducts and Evaluation of their Biological Potentials against Aedes aegypti

KEY WORDS:

Morita-Baylis-Hillman; Larvicide; Aedes aegypti

PAGES: 130
BIG AREA: Ciências Exatas e da Terra
AREA: Química
SUBÁREA: Química Orgânica
SUMMARY:

Currently, pathogens that have adapted to the changes imposed by nature continue to cause extensive socioeconomic damage and, especially, to human health. One example is the neglected tropical diseases caused by arboviruses, such as Dengue and Chikungunya. These pathogens, in turn, emerge from zoonotic cycles, mostly transmitted by the arthropod Aedes aegypti, including Zika and Chikungunya, for which there is still no vaccine available. Although there is a vaccine for some serotypes of Dengue, the high expansion of the vector has caused increasing levels of the disease in epidemics that have been occurring every 3 to 5 years. In view of this, this work aims to contribute to the planning and development of molecules with potential biological action through in-silico studies and application of the Morita-Baylis- Hillman reaction methodology, in order to collaborate in the control of the vector Aedes aegypti with the development of compounds with larvicidal potential.

BANKING MEMBERS:
Externo à Instituição - Verônica Diniz da Silva
Presidente - 2089941 - DIMAS JOSE DA PAZ LIMA
Externo ao Programa - 1820228 - RICARDO SILVA PORTO
Interno - 1366289 - THIAGO MENDONCA DE AQUINO