Banca de QUALIFICAÇÃO: DANYELLE CANDIDO SANTOS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : DANYELLE CANDIDO SANTOS
DATE: 20/10/2021
TIME: 09:00
LOCAL: webconferência
TITLE:

Antioxidant Evaluation and Bioelectrochemical Investigation of Nitrons

KEY WORDS:

Nitrons. Organic electrochemistry. Redox mechanism. Antioxidant Capacity

PAGES: 70
BIG AREA: Ciências Exatas e da Terra
AREA: Química
SUMMARY:

Nitrones are known for their ability to capture radicals and consequently reduce oxidative stress, this made them
promising synthetic antioxidants with high therapeutic potential. Because of this, they are being studied for the treatment
of several pathologies, such as cancer, stroke, Parkinson's and Alzheimer's diseases, among others. Since the
molecular mechanism of biological action of nitrones is not yet fully established, the present work aims to investigate
the bioelectrochemical and spectroelectrochemical behavior of nitrones and evaluate their antioxidant capacity. In order
to obtain data on the mechanism of reduction, oxidation, analysis of the stability of electrogenerated intermediates and
interaction with biological targets, such as DNA, in order to contribute to the elucidation of their molecular mechanisms
of biological action.

BANKING MEMBERS:
Externo à Instituição - AURO ATSUSHI TANAKA - UFMA
Interna - 1006306 - JADRIANE DE ALMEIDA XAVIER DOS SANTOS
Externo à Instituição - LEONARDO VIEIRA DA SILVA - IFAL
Presidente - 2120103 - MARILIA OLIVEIRA FONSECA GOULART
Externa ao Programa - 1320545 - THAISSA LUCIO SILVA
Interno - 1609640 - VINICIUS DEL COLLE