Banca de DEFESA: POLIANA DA CONCEICAO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : POLIANA DA CONCEICAO
DATE: 28/03/2022
TIME: 09:00
LOCAL: Google Meet
TITLE:

DEVELOPMENT OF ELECTROCHEMICAL SENSOR FOR ELECTROANALYSIS OF HOMOCYSTEINE VIA
MAGNETIC ELECTRODE MODIFIED WITH MOLECULARLY PRINTED POLYMERS

KEY WORDS:

Molecularly imprinted polymers; homocysteine; electroanalysis.

 

PAGES: 70
BIG AREA: Ciências Exatas e da Terra
AREA: Química
SUBÁREA: Físico-Química
SUMMARY:

The determination of homocysteine (Hcy) levels in cellular and intracellular tissue is an important diagnostic method
capable of predicting health risks, identifying diseases such as leukemia, Alzheimer's and cardiometabolic problems.
In this context, the improvement of more selective and sensitive analytical methods is of great relevance for the
detection of this compound. Given this, this work aims to develop electroanalytical strategies based on magnetic
electrochemical sensors for the separation and quantification of Hcy, an approach based on magnetically printed
molecular polymer (mag-MIP). The morphological and physical characteristics of the materials obtained were
investigated by scanning electron microscope (SEM), Fourier transform infrared (FT-IR) and vibrating sample
magnetometry (VSM). The physicochemical properties were also analyzed and compared with the respective magNIPs – control polymers without selective cavity. Subsequently, electrochemical studies using the cyclic voltammetry
(VC) technique were used to investigate the electrochemical behavior of Hcy in the graphite composite magnetic
electrode (m-GCE). Thus, the work carried out demonstrates the development of successful methodologies for
electrochemical sensors, relevant in clinical and medical analyzes with regard to the separation and quantification of
Hcy.

BANKING MEMBERS:
Externa à Instituição - ANA CAROLINE FERREIRA SANTOS - UFAL
Externa à Instituição - ANDRESA KATHERINNE ALBUQUERQUE DE ALMEIDA - UFAL
Externo à Instituição - AURO ATSUSHI TANAKA - UFMA
Presidente - 2120103 - MARILIA OLIVEIRA FONSECA GOULART
Interno - 1609640 - VINICIUS DEL COLLE