Banca de DEFESA: LARISSA THAIS OMENA DOS SANTOS

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LARISSA THAIS OMENA DOS SANTOS
DATE: 25/07/2023
TIME: 14:00
LOCAL: Sala de Reuniões do IQB
TITLE:

Mobile application for Human Milk donations and tracking its quality: a technology for donors in the city of MaceióAL

KEY WORDS:

Human Milk Bank; Microbiological analysis; mobile application; Physical-chemical analysis; Web System. 

PAGES: 145
BIG AREA: Ciências Exatas e da Terra
AREA: Química
SUMMARY:

As expressed human milk (EHM) is a food for vulnerable neonates, especially those admitted to intensive care units (ICUs), it is important to ensure its quality. Resolution 171/2006 of ANVISA (National Health Surveillance Agency) establishes the norms for the collection of donated Human Milk (HM) and the reference of its physical-chemical parameters (dirtiness, off-flavor, color, acidity in Dornic degrees and crematocrit ) and microbiological (total coliforms present/absent), for approval before and after pasteurization. ANVISA also recommends that all data from donors of EHM samples and the respective analysis results must be deposited in a secure information system. However, in addition to the presence of coliform contaminants, other groups of bacteria can be present and deteriorate the EHM. Thus, the purpose of this study was first to correlate the conditions of EHM collection with its physical-chemical and microbiological quality (raw and pasteurized), in order to then generate an application that aims to improve the logistics of collecting and transporting milk to the Human Milk Bank (HMB). It was initially a prospective, quantitative and cross-sectional study, conducted at the HMB of the University Hospital “Professor Alberto Antunes” at the Federal University of Alagoas (HUPAA/UFAL) and at the “Laboratório de Bioquímica do Parasitism and Microbiologia Ambiental” (LBPMA) at the Institute of Chemistry and Biotechnology (IQB) at the same university, involving 32 donors. To this end, there was an analysis of the collection situations through recorded interviews, using a form of health conditions and collection, also containing the "Edinburgh Depression Scale" (EDPS) and prepared according to the "Global Human Milk Network". In addition, the isolation and quantification of heterotrophic bacteria (mesophilic, thermophilic, psychrophilic) and thermoduric bacteria from the EHM samples previously approved in the physical-chemical tests were carried out. From the questionnaire, it was extracted that 28.13% of the donors presented a significant increase (p<0.001) in the frequency of weekly postpartum indisposition, 68.75% described a significant decrease (p<0.001) in sleep time in relation to the period pre-pregnancy, 56.25% reported some problem with breastfeeding, 21.88% showed signs considered depressive and 60% did not discard the first drops of milk before collection. From the analyses, it was found that the crematocrit did not vary significantly in relation to data obtained in the interviews with the donors, such as the pre-gestational BMI (body mass index), the donor's age and the age and classification of the newborn. All samples passed the total coliform test, and there was no significant difference between samples from domestic and non-domestic donors (and their replications) in terms of low counts of mesophilic and thermophilic bacteria. In view of these cross results, a mobile application called Lactababy-Maceió was formulated, to attract potential donors, record data from collections at home or not, guide teleconsultations, record and forecast transport, processing and distribution of the LHO that was considered adequate by the evaluators, obtaining 80% in the degree of agreement.

BANKING MEMBERS:
Externo(a) ao Programa - 3195712 - AMANDA LYS DOS SANTOS SILVA
Presidente - 1121343 - ANA MARIA QUEIJEIRO LOPEZ
Interno(a) - 1997465 - DANIELA SANTOS ANUNCIACAO