Banca de DEFESA: INGRID VIEIRA FERNANDES MONTEIRO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : INGRID VIEIRA FERNANDES MONTEIRO
DATE: 26/02/2021
TIME: 09:00
LOCAL: Vídeoconferência
TITLE:

DEVELOPMENT OF A NANOSYSTEM TO CONTROL RINCOPHOROL AGGREGATION PHEROMONE RELEASE”

KEY WORDS:

Rhincoforol, polymer / lamellar silicate nanocomposite; modified release

PAGES: 68
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUBÁREA: Farmacotecnia
SUMMARY:

Rincoforol is an aggregation pheromone applied as bait in traps to capture Rhynchophorus palmarum. The challenge of its commercialization is in the form of packaging, which does not guarantee its integrity during the whole period of application nor modulates its release rate. Therefore, the formulation of this pheromone in a modified release device is recommended, ensuring protection against degradation and release at appropriate levels. Therefore, the present work aims to develop a modified release device of the polymer/silicate lamellar nanocomposite (PLN) type, composed of alginate and bentonite, providing protection to Rincoforol and release at appropriate levels. Films and gels were prepared through ionotropic gelation and different silicate concentrations. The structural analysis of the nanocomposite was performed through X-ray diffractometry and infrared spectroscopy. The film product was evaluated for adhesiveness, swelling index and tensile strength. DRX and FTIR elucidated the interaction between the matrix components. The adhesiveness of the films was lost according to the applied obtaining methodology. The addition of silicate to the formulation resulted in an increase in the mechanical resistance of the polymer, resulting in lower water uptake and greater resistance to traction. The matrix, until then, shows promising as a modified release device. It is also expected to complete stability studies of Rincoforol adsorbed to the matrix and release kinetics to ensure that the nanocomposite is suitable for modified release of this pheromone.

BANKING MEMBERS:
Externo à Instituição - ARÍDIO MATTOS JUNIOR - UFRJ
Externo ao Programa - 1119939 - ANTONIO EUZEBIO GOULART SANTANA
Interna - 1527220 - CAMILA BRAGA DORNELAS
Externo ao Programa - 2149347 - HENRIQUE FONSECA GOULART
Interno - 1653558 - LUCIANO APARECIDO MEIRELES GRILLO