Banca de DEFESA: ROBERT RODRIGUES ALVES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : ROBERT RODRIGUES ALVES
DATE: 29/04/2022
TIME: 14:00
LOCAL: Vìdeoconferência
TITLE:

DEVELOPMENT OF CHITOSAN NANOPARTICLES LOADED WITH ESSENTIAL OIL FROM Syzygium aromaticum (CLOVE)

KEY WORDS:

nanoparticles; chitosan; Rhynchophorus palamarum; Tribolium castenum; Syzygium aromaticum.

PAGES: 91
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

In this scientific research, the synthesis of nanoparticles was performed using a chitosan extracted from Rhynchophorus palmarum, considered an important insect pest of palm trees. First, chitin was extracted and converted into chitosan, through a deacetylation reaction. Chitin is the main structural component of the cuticle of arthropods and from it chitosan is produced, which has several applications in several areas, such as pharmaceutical, food and agriculture. Physicochemical analyzes were performed to characterize these products: Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD) and their yields, obtaining excellent results. Then, with the chitosan obtained, the development of nanoparticles encapsulated with essential oil of Syzygium aromaticum (clove) was carried out through the ionic gelation method. Analysis was performed by Gas Chromatography coupled with a mass spectrometer (GC-MS), which revealed a content of 90.71% of eugenol, the major substance responsible for the insecticidal properties of the essential oil. With the nanoparticles, tests were carried out on zeta potential, average particle size, FTIR, Scanning Electron Microscopy, encapsulated oil content and release test, through UV-VIS, in addition to insecticidal tests (repellence and mortality) in adult insects of the species Tribolium castaneum, considered an important pest of stored grains (rice, corn, wheat, among others). The results revealed that the encapsulation of the oil occurred effectively and that the concentration of essential oil was able to repel the insects, but it was not enough to cause their mortality. The development of nanoparticles with clove essential oil, indicate a promising strategy as a bioinsecticide, being an alternative to chemical insecticides, which among the problems, can affect human health.

BANKING MEMBERS:
Interno - 1553302 - IRINALDO DINIZ BASILIO JUNIOR
Interno - 1653558 - LUCIANO APARECIDO MEIRELES GRILLO
Externa ao Programa - 1230086 - MEIRIELLY KELLYA HOLANDA DA SILVA
Externo ao Programa - 1653165 - VALTER ALVINO DA SILVA