Banca de DEFESA: RAYANE CAROLINE MEDEIROS DO NASCIMENTO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : RAYANE CAROLINE MEDEIROS DO NASCIMENTO
DATE: 23/03/2022
TIME: 14:00
LOCAL: Plataforma online (Google Meet)
TITLE:

Dissociative anesthesia and inflammatory mediation of donkeys under Vulnerability submitted to orchiectomy

KEY WORDS:

northeastern donkeys, anesthetic protocol, inguinal access, recovery.

PAGES: 129
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

This research presents the results obtained in the research on dissociative anesthesia and inflammatory mediation of vulnerable donkeys, removed from slaughter in the state of Bahia, submitted to inguinal and scrotal orchiecthymias. The main objective of this research was to evaluate dissociative anesthesia with Xylazine (1mg/kg), Ketamine (2mg/kg) and Midazolan (0.4 mg/kg), combined with testicular anesthesia with 2% lidocaine, measuring the anesthetic quality, duration of recovery and applicability. It presents as chapters: The historical context of the importance of donkeys in the Northeast; Donkey analgesia: The state of the art; Type II rectal prolapse: Report of three cases; and Combination of midazolam and ketamine in the anesthesia of donkeys submitted to orchiectomy: physiological effects and evaluation of anesthetic quality. Were 30 animals were selected, kept in an extensive system (without any supplementation), under vulnerability, in a property located in the sertão region of Bahia, in the municipality of Canudos. The protocol performed was the same for all animals, and consisted of preanesthetic medication (MPA) through sedation with xylazine (1 mg\kg IV); local block with 2% lidocaine of the testicular parenchyma (10 mL on each side) and 5 mL bilaterally in the skin regions to be incised. The animals were submitted to ketamine induction (2 mg/kg) and midazolam (0.4 mg/kg) and placed in the supine position, with inguinal orchiectomy performed. The heart rate (HR) and respiratory rate (RR) were measured at four times, being at the moment immediately before premedication (T1), right after induction (T2), 10 (T3) and 15 minutes after induction (T4). Anesthetic quality assessment was performed based on the variables defined in the study, classifying by scores (0-3) on sedation, anesthetic induction and maintenance. Surgery time (from skin incision to closure with suture), time to sternal recumbency and return to quadrupedal position were measured for the purpose of standardizing behavior. At the end of the surgery, the animals were submitted to fluid therapy with Ringer's solution with lactate (20ml/kg). The proposed protocol did not lead to significant physiological changes during anesthesia of mean surgical procedure of sixteen minutes related to orchiectomy. However, it was noted that a third of the animals did not present sufficient sedation with the xylazine dose of 1 mg/kg, which may have caused a lower resistance in anesthetic induction in almost a quarter of the sample and need for reinforcement in anesthetic maintenance in 40% of donkeys. From the research, the safety of the described protocol is proven, with the need for new research to see if increasing the dose of xylazine would not bring better anesthetic quality in physiological effects not satisfactory to the species.

BANKING MEMBERS:
Presidente - 1670912 - PIERRE BARNABE ESCODRO
Externa à Instituição - ISABELLA DE OLIVEIRA BARROS
Externa à Instituição - TALYTA LINS NUNES