Banca de QUALIFICAÇÃO: EMMANUELE SANTOS ALBUQUERQUE

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : EMMANUELE SANTOS ALBUQUERQUE
DATE: 26/05/2021
TIME: 08:00
LOCAL: Apresentação via Google Meet
TITLE:

Adherence to Drug Therapy in patients with Systemic Lupus Erytheamstreated treated at a University Hospital

KEY WORDS:

Medication Adherence; Systemic Lupus Erythematosus; Chronic Disease.

PAGES: 30
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

INTRODUCTION: One of the points considered most important for the success of a treatment is adherence to the prescribed therapy. The World Health Organization (WHO) points out that patients with chronic diseases are potential candidates for inadequate follow-up of the proposed drug therapy, which hampers the achievement of the desired results, putting in doubt, for example, its efficacy. In the group of chronic diseases is Systemic Lupus Erythematosus (SLE), which also corresponds to an inflammatory, multisystemic, immune-mediated disease. Low adherence to SLE can lead to disease activity, causing organic damage, increasing the number and length of hospital stays, reducing the quality of life of this patient, culminating in a high risk of morbidity and mortality, work and school absenteeism, generating a great impact psychosocial and economic aspects of patients and their social environment. OBJECTIVES: To verify the prevalence of Adherence to Drug Therapy (TMJ) among patients with Systemic Lupus Erythematosus (SLE) and the factors associated with it. MATERIAL/METHOD: exploratory, descriptive, cross-sectional study, carried out at the SLE Clinic of the Rheumatology Service of Hospital Universitário de Alagoas, Brazil. The sampling method used was non-probabilistic for convenience and the sample consisted of 116 patients in outpatient care. Data collection took place through the application of the Sociodemographic Questionnaire, the Brazilian Economic Classification Criterion of ABEP, MAT (Treatment Adherence Measure), SF-12, SLICC, SLEDAI and analysis of medical records. Descriptive and inferential statistical analysis was performed. RESULTS: Demographic and social data showed that 64.7% of the sample declared themselves brown, with a mean age of 36.5 (± 11.30), with the majority being female (95.7%). Regarding the sample's schooling, 50.9% had completed high school; the income of 46.6% of the sample being approximately up to a minimum wage. Regarding the treatment regimen, 58.6% of the sample had polymedication. The prevalence of adherence was 55.2%. The statistical tests used in this study showed an association between the variable adherence and time since diagnosis (p <0.033), headache (p <0.014), physical exercise (p <0.005) and difficulty following the treatment (taking medication and / or performing exams and / or going to consultations) (p <0.000). CONCLUSION: The study data indicated that adherence to drug therapy in SLE is a complex and multifactorial phenomenon. The identification and analysis of the factors that can lead to non-adherence to drug therapy, can allow the development of health actions aimed at reducing barriers in treatment, as well as care costs and, mainly, promoting better perspective and quality of life for the patient.

BANKING MEMBERS:
Interno - 1137473 - CLAUDIO TORRES DE MIRANDA
Interno - 1791653 - FLAVIO TELES DE FARIAS FILHO
Interna - 2370894 - MICHELLE JACINTHA CAVALCANTE OLIVEIRA
Presidente - 1483526 - THIAGO SOTERO FRAGOSO