Banca de DEFESA: MYRA JUREMA DA ROCHA LEAO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MYRA JUREMA DA ROCHA LEAO
DATE: 30/08/2021
TIME: 14:00
LOCAL: google meet
TITLE:

Epidemiological profile, risk factors related to breast cancer in patients in Alagoas

KEY WORDS:

Breast neoplasms, prognosis, risk factors

PAGES: 22
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

Abstract: Objective: To analyze the epidemiological profile of cancer patients undergoing treatment for breast cancer in the state of Alagoas, and to investigate the involvement of risk factors and prognoses associated with the disease. Methods: A cross-sectional, retrospective and analytical, with the use of secondary data from medical records, and prospective with the completion of questionnaires applied to patients in outpatient follow-up at Santa Casa de Misericórdia de Maceió/Al.Information contained in the medical records of this institution regarding patients with outpatient breast cancer treated in two periods was collected: January and February 2019 and the corresponding months of this year, and completed forms. Patients in outpatient care were also recruited in a probabilistic manner for convenience and questionnaires were completed. In these forms, the primary variable was breast cancer and secondary variables were: gender, age, address, schooling, histological type, clinical staging and immunohistochemical classification, neoadjuvance, adjuvence, radiotherapy, radical surgery and conservative surgery. To obtain the complementary clinical variables, the questionnaires were applied, containing as additional secondary variables: weight, height, body mass index, family history for cancer, personal history for cancer and benign breast disease, smoking, alcohol consumption, early menarche, late menopause, nullparity, breastfeeding, use of hormonal therapy, use of contraceptive, sedentary lifestyle. This data was transferred to a Microsoft Office Excel 2020 spreadsheet and statistical analysis was used in the SPSS Statistics Version 26 program. The descriptive data were operationalized through tables and graphs, means, frequencies, standard deviation, and inferential statistics with chi-square tests of independence for the analysis of nominal qualitative variables and ordinal qualitative variables and spearman's correlation was used for the analysis of ordinal qualitative variables. Results: A total of 110 female patients (67 forms and 43 questionnaires) were evaluated. The mean age was 52.99 years. Most women were over 50 years of age (55%), followed by 35-50 years (37.6%) and eight (7.3%) patients were under 35 years of age. For the most part (51%) the patients were from the interior of the state, single (68%) and had a complete middle education (40%). Regarding topography, fifty-six patients (51.4%) right and 48.6% had tumor on the left. With regard to staging, for the most part (55%) presented staging I or II and 45% had staging III or IV. Among the histological types, Infiltrating Ductal Carcinoma was the most common (97%). In 60% of the cases, radical mastectomy was the treatment instituted. 2019 was the year in which most surgeries occurred (27.3%), followed by 2020 (24.5%) and 2018 (11.8%). Neoadjuvant chemotherapy was used in 46% of patients, while adjuvant in 51.6% of cases. Forty-five patients (61.6%) radiotherapy, 10% used anastrazole, 27.7% tamoxifen and 15% Herceptin. Among the risk factors, alcohol consumption was the most found (27%), followed by obesity (17.3%) and sedentary lifestyle (16.4%). Of the total number of patients evaluated, lactation was identified in 27.3% (n=30), in addition, only 2.7% of the patients evaluated were nulliparas. Regarding the histological subtype, luminal subtype B was the most common in patients under 35 years of age, as well as in patients aged between 35 and 50 years. In the population over 50 years of age, the luminal subtype A was the most frequent. Conclusions: The data of the present study corroborate those found in the literature, presenting modifiable risk factors (obesity, sedentary lifestyle, alcohol consumption, use of oral contraceptives), present in this population, but not mostly. A curious fact is the finding of breastfeeding in most women who had breast cancer, considered a protective factor. Thus, it is considered that the knowledge of the epidemiological profile of a disease, such as breast cancer, helps health professionals regarding the characterization of a target population and, consequently, regarding the elaboration of targeted educational strategies, with preventive and self-care measures.

BANKING MEMBERS:
Externo à Instituição - CARLOS AUGUSTO DE OLIVEIRA CAVALCANTI - CESMAC
Externa à Instituição - ROBERTA LIMA - CESMAC
Interna - 2272670 - ALINE CAVALCANTI DE QUEIROZ
Presidente - 2269479 - CAROLINNE DE SALES MARQUES
Externo à Instituição - FREDERICO THEOBALDO RAMOS ROCHA - NENHUMA
Interna - 2370894 - MICHELLE JACINTHA CAVALCANTE OLIVEIRA