Banca de DEFESA: TADEU PEIXOTO LOPES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : TADEU PEIXOTO LOPES
DATE: 29/09/2021
TIME: 18:00
LOCAL: google meet
TITLE:

Evaluation of the prevalence of chronic kidney disease in patients with chronic obstructive pulmonary disease.

KEY WORDS:

Chronic kidney disease, chronic obstructive pulmonary disease, microalbuminuria

PAGES: 30
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

The consonance between Chronic Kidney Disease (CKD) and Chronic Obstructive Pulmonary Disease (COPD), two age-related conditions, has fundamental clinical implications and prognosis. The age effect on renal and pulmonary function increases the complexity of the interaction between the kidney and lung. The aim of this trial is to clarify the pathogenic mechanisms that establish COPD associated with increased prevalence of CKD, since there are several gaps in lung-kidney interaction, which requires further research for such analysis.

A cross-sectional observational study was conducted with patients previously diagnosed with Chronic Obstructive Pulmonary Disease (COPD) from the Professor Alberto Antunes University Hospital (HUPAA) in Maceió-AL, northeastern Brazil, from September 2020 to March 2021. specific symptom questionnaire (MMRC) in addition to the analysis of the last spirometry. After data collection, these patients were categorized and divided according to the gold 2019 classification groups (A, B and C/D). Serum creatinine, creatinine and albumin were dosed in an isolated urine sample in order to estimate the glomerular filtration rate using the ckd - EPI 2009 formula and to define the presence of albuminuria (> 30mg/g albumin/creatinine).

There were 45 patients analyzed in our study, of this total, 24 were classified as GOLD A, 13 men and 11 women, with ages ranging from 53 to 83 years, 4 diabetics, 11 hypertensive patients, mean GFR 75.3 ml/min/1.73 m2 and mean microalbuminuria of 33.4 mg/dl. In GOLD B were 7 men and 2 women, ages ranging between 53 and 90 years, 2 diabetics, 7 hypertensive patients, mean GFR of 74.2 ml/min/1.73 m2 and mean microalbuminuria of 152.8 mg/dl.

In the GOLD C/D group, we classified 9 men and 3 women, ages ranging from 55 to 88 years, 1 diabetic, 8 hypertensive, mean GFR of 75.7 ml/min/1.73 m2 and mean microalbuminuria of 149 mg/dl.

The results obtained when we evaluated the GOLD relationship with glomerular filtration rate was not significant, but the GOLD relationship with microalbuminuria was significant, evidencing higher in the GOLD B and GOLD C/D groups compared to GOLD A.

BANKING MEMBERS:
Interno - 1506475 - ALYSSON WAGNER FERNANDES DUARTE
Interno - 2361727 - CARLOS ALBERTO DE CARVALHO FRAGA
Externa à Instituição - JUSSARA ALMEIDA DE OLIVEIRA BAGGIO
Interna - 7530212 - MERCIA LAMENHA MEDEIROS
Interno - 1108003 - REGINALDO JOSE PETROLI
Presidente - 2154281 - RODRIGO PEIXOTO CAMPOS