Banca de DEFESA: LARISSA DA SILVA PINTO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LARISSA DA SILVA PINTO
DATE: 21/06/2022
TIME: 19:30
LOCAL: Google Meet
TITLE:

Impact of anxiety and depression on quality of life in chronic rheumatologic diseases in childhood

KEY WORDS:

Anxiety. Depression. Quality of life. Childhood.

PAGES: 35
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

INTRODUCTION: Pediatric systemic lupus erythesis (pLES) and juvenile idiopathic arthritis (JISA) are chronic rheumatologic diseases that affect the infant age group. In addition to organic systemic impairment, these conditions are associated with the occurrence of depression and anxiety, causing a negative impact on quality of life. OBJECTIVE: To trace the sodium demographic profile; Estimate anxiety and depression rates in patients with pediatric systemic lupus erytheams (pLES) and juvenile idiopathic arthritis (JIS); Measure the level of quality of life; Correlate anxiety and depression to the level of quality of life; Associate anxiety and depression with disease activity; To compare quality of life in groups with and without disease activity. MATERIALS AND METHODS: Observational study and cross-sectional study. The sample was selected by convenience, composed of patients with pLES and AIJ followed by the Pediatric Rheumatology outpatient clinic of the Professor Alberto Antunes Hospital, a tertiary hospital in a capital of the Northeast. We included patients of both sexes aged between 7 and 17 years whose parents signed the Informed Consent Form (Informed Consent). Data were obtained through a face-to-face interview. The variables of analysis were: socioeconomic data; anxiety (via the Screen for child anxiety related disorder- SCARED) questionnaire, depression (from the Children's Depression Inventory - CDI) instrument, quality of life level (using the Pediatric Quality of Life InventoryTM Scale Version 4.0- PedsQualis ), activity of p Les (through the modified systemic lupus erythematosus disease activity index- 2k - SLEDAI) and activity to AIJ (from the Clinical Juvenile arthritis disease activity score- cJADAS score). The analyses were made with the help of the statistical package JAMOVI version 1.6.3.0. Descriptive data are represented by means, median, frequencies, standard deviation and interquartile interval. The Shapiro-Wilk test was used to verify the normality of the distribution of the variables. The comparison between two means was made by the t-Student test. P< 0.05 values were considered statistically significant. Spearman's test was used to correlated nonparametric variables. For the association of two categorical variables, fisher's chi-square and exact tests were selected. RESULTS: There were 26 participants with a mean age of 11.2 ± 2.94 years, the majority of which were female (80.8%), coming from the interior of the state (69.2%) and belonging to economic class 6 (73.1%). Anxiety and depression rates were 50% and 11.5% respectively. The average quality of life was 70.6 + 18.1. There was a negative correlation of anxiety to the domains of emotional quality of life (rho= -0.707, p < 0.001) and school (rho= - 0.532, p < 0.005). Depression showed a negative correlation to the physical (rho= -0.632; p< 0.001), emotional (-0.564; p < 0.003) and school (-0.613; p< 0.001) domains of quality of life. Disease activity was not associated with anxiety, x 2 (1)= 1.39 (p=0.238) or depression x 2 (1)= 0.399 ( p=0.580). In this study, those with disease activity (M = 69.5; SD = 18.6), obtained similar means of quality of life in relation to those without disease activity (M = 71.7, SD = 18.2) with no significant difference (p=0.763). CONCLUSION: The impairment in the emotional, school and physical domains of quality of life in patients with rheumatologic diseases in childhood is correlated with depression and anxiety. There is no association between disease activity and quality of life and mental disorders evaluated in this study.

BANKING MEMBERS:
Interna - 2272670 - ALINE CAVALCANTI DE QUEIROZ
Externa ao Programa - 1627935 - AUXILIADORA DAMIANNE PEREIRA VIEIRA DA COSTA E SILVA
Interno - 1791653 - FLAVIO TELES DE FARIAS FILHO
Externo à Instituição - ROBERTO CORDEIRO DE ANDRADE
Interno - 2154281 - RODRIGO PEIXOTO CAMPOS
Presidente - 1483526 - THIAGO SOTERO FRAGOSO