Banca de QUALIFICAÇÃO: TENILDO LOPES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : TENILDO LOPES
DATE: 30/01/2023
TIME: 19:30
LOCAL: Google Meet
TITLE:

PATIENT WITH SISTEMIC LUPUS ERYTHESIS AND ITS ASSOCIATION WITH FATIGUE, CLINICAL PARAMETERS AND DRUG THERAPY

KEY WORDS:

Systemic lupus erythesis, fatigue, functional capacity and drug therapy

PAGES: 35
BIG AREA: Ciências da Saúde
AREA: Educação Física
SUMMARY:

INTRODUCTION: Systemic Lupus Erythesus (SLE) is an autoimmune disease that affects several organs and is associated with fatigue. In addition, the patient of this disease suffers losses in daily activities with impairment in functional capacity with low level of muscle strength and postural instability. In addition, with the evolution of the disease, there is an increase in the risk of fall and low physical conditioning. OBJECTIVES: To verify the level of fatigue in patients with systemic lupus erythesus; Evaluate the level of handgrip strength in patients with systemic lupus erytheamsum; Analyze functional capacity in patients with systemic lupus erythesus; Evaluate the strength of the lower limbs in patients with systemic lupus erythesus; Assessing the handgrip strength in patients with systemic lupus erythesus MATERIALS AND METHODS: An observational, cross-sectional study was performed in patients with confirmed diagnosis Systemic Lupus Erytheamus (SLE) followed at the Professor Alberto Antunes University Hospital – Federal University of Alagoas in the city of Maceió-AL. The sample was composed of people from 18 years of age, in which all signed the Free Consent and Informed Consent Term (TCLE). The variables of analysis were: anthropometric measurements such as weight, height and BMI; systemic lupus erithematosus disease activity index); functional capacity through handgrip tests, sitting and lifting of the chair 5 times and static balance; verification of the presence of fatigue through the Fatigue Severity Scale; verification of covid-19 contagion and post-covid-19 sequelae through self-report and socio-demographic questionnaire. Descriptive analyses were performed using mean, standard deviation, relative and absolute frequency for continuous variables and percentage for binary variables. The Shapiro-Wilk test was used to verify the normality of the distribution of continuous variables. In the normal condition of the data, the comparison between two means will be made by the t-Student test. In the case of non-normality of the data, the Mann-Whitney test was applied. P< 0.05 values were considered statistically significant. FINDINGS; The sample presented a predominance of 100% female, mean time of disease installation 9.1 years, no patient reported using alcohol or smoking, 23% reported having hypertension and 10% diabetes, mean age of 40.1±12.5, weight 66.2±13.1, BMI 26.0 ±4.9, regarding physical activity practice 75% reported not doing any type of exercise,  80% of the patients revealed to have taken the covid vaccine on average 2.6 ±0.9, among the functional capacity test 92% of the patients were above the cutoff point of 13 seconds in the sit and lift test 5 times, in the static balance test only 10% presented difficulties in the monopedal phase and could not complete the test,  in the right handgrip test value in kilos in the right hand 10.0 ±6.3 left hand 9.1 ±5.9, among the verification of the fatigue severity scale the mean value was 35.5 ±16.8, in the items that focus on constant physical performance, obligation, responsibilities, disabilities and in the social and family relationship the mean value was above the cutoff point 4.0,  among the medications used were Hydroxychloroquine and Azathioprine CONCLUSION: the results of the present study demonstrate that the presence of fatigue in the activities of daily living of patients with systemic lupus erytheams, has impaired their obligations and responsibilities especially in those who depend on the performance of some physical effort, the presence of fatigue also influences the low level of physical activity increasing body composition and the emergence of new diseases  hypertension and diabetes.

BANKING MEMBERS:
Interno(a) - 1791653 - FLAVIO TELES DE FARIAS FILHO
Interno(a) - 2370894 - MICHELLE JACINTHA CAVALCANTE OLIVEIRA
Presidente - 1483526 - THIAGO SOTERO FRAGOSO
Interno(a) - 1728726 - VALFRIDO LEAO DE MELO NETO